I have a neighbor who recently returned to 3 days a week at the office, his wife is at 4 days. They're basically doing the same work they've been doing the past two years with the commute or the ability to schedule things like doctor's appointments and such around working at home.
My wife is permanently working remote and what I'm seeing it can be more stressful at times. Most of the times her day is filled with meetings (her position involves a lot of strategy meetings) with no real down time. Most of the staff is in the building one day a week and she says she misses that a bit. There a lot of issues that can be straightened out wit just a quick chat in the coffee room, or on the way back to the cubical.
Before COVID her day might consists of meetings anywhere from Wixom to Ann Arbor, Downtown Detroit, Lansing, etc. The drive would give her time to unwind and digest the conversations from the meetings. Of course the 12 hour she makes it a bit tough now except for the trips to Michigan every month or so now.
Bottom line I don't think there is a perfect solution.
(At least she didn't have to go to Mackinac Island this week)