If you have a RH batter with a reasonably high OBP against RHP, you do want to put a LH batter behind him to optimize his chance of going 1st to 3rd on a another base hit. Most managers like alternating right and left hand hitters, so that sort of leaves you with a preference to go RH in the lead-off spot and then LH in the 2 hole - but if your LHH is you best OBP by a significant margin (often true), he's still your lead off hitter. The overall is probably too close to a toss-up to worry about it a lot.