gehringer_2

One of the patterns with anti-virals is that they often have to be administered so early in the course of the infection that the patient is not yet aware they are infected. That can limit their practical usefulness, esp for drugs that require a prescription which means contacting or visiting a doctor or clinic. This new Merck product is described as effective given 'within 5 days of infection'. Hopefully that is a big enough window for people to get effective use of it - assuming it's approved.

Y U P !

TBH, outside observer's have had serious criticisms of the way FoMoCo has been run throughout WCF's Jr's tenure as COTB. There has been a bit of a crises to crises pattern with some poor CEO tenures (Hackett, Nasser) alternating with management 'rescues' Peterson, Mullaly, and now Farley is getting a lot of positive press and the stock value heading up again.

I think the key starts with the Larkin line though. You have to find the right mates for him, because when that line clicks, it elevates to where the other team has to start worrying about match-ups, then it becomes easier right on down for the 2nd and 3rd Wing lines. Get Larkin's line-mates right and the rest all follows. I wish he could be more effective playing with whoever he gets thrown out there with but that doesn't seem to be the way it goes.

yup - Snitker was/is managing to win one out of three - which is probably the right strategy. There are no style points awarded for winning in less than 7.

The thing with SFH is the same with WCF, maybe they will succeed, but there just isn't any kind of resume there of successfully building/managing any kind of competitive organization. Now that's not the be all and end all, she *might* turn out to be good at it, and plenty of people with a lot of outside success have been terrible sports owners - our own Dan Gilbert not the least with the Cavs and Tom Monahan with the Tigers. And for that matter WCF Jr has/had plenty of management experience when he was advising his father and that sure didn't seem to do any good. Still, all-in-all your odds are probably better with an owner that has a resume of accomplishment building or running something. SFH is just another 'maybe we get lucky this time.' That's not her fault, it just is what it is.

All true. I guess what triggered me was the way it was put: "Campbell has a guy that tells him when to go for 4th down." Well no, Campbell may have a guy that gives him an overview of what the most common outcomes in a situation may be, but Campbell better be doing all the things you describe and using that as one factor in a more complex decision analysis and not just nodding his head!

The more general point raised by D Karch this morning is was the time. They were down to roughly 1 play (13sec?). So throw it into the end zone or kick it should have been the choices. If they had made the sneak where does that leave them? They still have to kick or take a shot into the end zone. IOW the clock was the bigger constraint than getting the 1st down.

no, because what was happening right at the beginning had nothing to do with what any government or local population was consciously doing because no-one knew what they were doing. The death/incidence rates early on had to do almost completely with how international travel patterns first distributed the virus around the country and where it first found dense low health populations. NYC apparently hit because of connections to Italy (don't remember why Italy was one of the first hit but it was...) and Detroit apparently because of auto industry connections to Wuhan.

LOL - I think the sports world has gone insane. You can do all the analytics back to 1933 and it still doesn't tell you whether that particular day on that field, *your* RT is handling *their* LDE or instead getting manhandled by him better than your own offensive co-ordinator looking at the play by play shots in real time. There are some things in life where each event is essentially a 'one of' and statistical analysis on those things can only have limited value. Could be why the Lions' results look so random? Or put another way, the analytics can tell you what the added win probability is for the average two teams in that situation, but you still have to decide for yourself on that play if your team and the other team look anything like average that day - and that is always a judgment call on a set of *unique* circumstances and matchups for that play. wonder if we are getting to the point where selling analytics to sports teams has become enough of a business in it's own right that it's becoming subject to the same over-hyping kind of marketing as other businesses.

well, there is bad, then there is Lion's bad! No matter how many years you've had to prepare, it's still hard to expect Lions's bad.

The argument is whether the market actually captures cost accurately or fairly or even 'justly.' Obviously books have been written arguing all this stuff backward and forward, but suffice it to say that 'the free market' is an intellectual idealization that exists exactly nowhere, so any any real world argument that invokes it is immediately suspect....

trap game next week - could be a big let-down after this one. I heard Cade stepped up and put the loss on himself. Did his coach make a point of contradicting him (I guess we don't find out until at least tomorrow....) or will his coach let him get more or less thrown under the bus for a game when the D gave up 37?

well, it's always nice to finally achieve clarity on long unsolved riddles. 👳‍♂️

It strikes me they couldn't have done a very good job on UDFA's and searching the cut down lists. There had to have been at least a few players better than this combination who are seriously threatening to go 0/17. Even if you put up a whole team made up of each team's last cut you should be able to at least win a couple. Or even worse to contemplate, this coaching staff actually isn't better than Patricia....

Walmart dithered for years before they finally opened the store in Washtenaw county near Ypsi. They closed it last year. I guess there is still one in Saline - never been there.

Fabbri was certainly a bad match with Larkin and Raymond. Larkin's limitation seems to that he can't adjust down to the players he is stuck with. If they can't all get on his wavelength his productivity doesn't just fall, it craters.

Hey - the line forms on the left, buddy!

exactly. It's completely logical to give the kid extended time with a good lead and keep the experienced guy at the helm when the pressure is high. But not Harbaugh - no, he has to try to be clever and keep doing the 'unexpected' - that is stuff that he thinks is unexpected even if we've all come to completely expect and anticipate Harbaugh's idea of the 'unexpected'. In the meantime he keeps learning (or really, not learning) that the reason stuff he is doing *should* be unexpected is because they are generally losing strategies. He seems to be fine man, and I give him a lot of credit for being a coach that seems to do want to do right by players - his support of the easier transfer rules where he is at odds with most coaches is an example -- and all the extra outside experiences he has tried to provide his players, but my lord, whatever his other virtues, he is such a terrible field general.

2:1 Cade goes through the portal. He can see McCarthy is the golden boy. If I were Cade I'd be tired of criticisms and a coach that didn't feel he needed me in the game in critical situations. Objectively we can argue whether he had actually done enough to merit that level of confidence, but that's immaterial to whether the young man decides he would rather play somewhere else.

IDK, at the time Harbaugh was the hottest thing on the coaching market - past UM resume or not. It may have given him more rope, but Covid and financial considerations probably have more to do with why he is still here. I don't think R Rod was done in so much because he wasn't an Alum of the program as much as because Carr (and so in turn his loyalists) just plain didn't like him and had wanted someone else. As it transpired, maybe they did know more about him personally than the people that hired him. In any case I don't know how you separate how much of that dislike would have been any different if he had happened to have played football or coached here before. The 'Michigan Man' thing may be a convenient wrapper for the narrative and all things being equal I'm sure it figures in the overall story, but I think on the whole it's overrated. While playing to a market is certainly in their handbook, major college admins are in general not romantic people. The funny thing is that even as Bo most famously used the term, it had nothing to do with being an alum of the U or the program because Frieder certainly already was - he was the coach. Bo's issue wasn't where Frieder had come from, it was where he had decided to go - as in he had decided to leave. To Bo, all that made Steve Fisher the "MichiganMan" as opposed to Frieder was that he was 'loyal' and Frieder had not been. Had nothing to do with either person's history. So the whole damn Bo historical "Michigan Man as a 'son' of the school" meme is based on nonsense.

Can't. Fielding Yost is about to become another face erased from the team pictures. (This one's probably merited though...)

are we still holding out any hope for McIsaac, or is he a write off? Smith's security is that he's about the closest thing they have to an enforcer.

Maybe one's roots have found the sewer line......💰

upgrades needed for Fabbri and Gagner. Velano could be one.